Biogena Nutrifem P-M-S Formula®
60 capsules · 2 capsules per day
AD1131373
Product description
Multi-ingredient formula with calcium, magnesium, iron, zinc, B vitamins and vitamin D3 plus chasteberry, ginkgo and maritime pine bark extract.
Assessment by Oliver Fröhner
Micronutrient expert & Food Coach
Product character
The product combines several minerals, vitamins and botanical extracts rather than focusing on one nutrient. Magnesium, iron, zinc, vitamin D3 and the comparatively high vitamin B6 intake are particularly relevant from an orthomolecular perspective.
Formula & transparency
- Ingredients list fully checked
- Without microcrystalline cellulose according to the fully reviewed ingredient list
- Without silicon dioxide according to the fully reviewed ingredient list
- Product data reviewed within the freshness period
Points to consider
- A current product- or batch-specific notice is available.
Data basis
- Lab report available but not marked as reviewed
- HPMC/hydroxypropyl methylcellulose is declared.
Summary by Oliver Fröhner
Multi-ingredient formula with calcium, magnesium, iron, zinc, B vitamins and vitamin D3 plus chasteberry, ginkgo and maritime pine bark extract.
Manufacturer information and Oliver Fröhner’s editorial assessment are presented separately. Data checked: 16 Sep 2026.
Active ingredients & NRV
Active ingredients
Ingredients & additives
Calciumcarbonat, Biogena Viersalz®-Komplex (Magnesiumcitrat, Magnesiumoxid, Magnesiumgluconat, Magnesiumcarbonat), Hydroxypropylmethylcellulose (Kapselhülle), Füllstoff: Cellulosepulver; Ginkgo-biloba-Extrakt, Zinkpicolinat, Eisenbisglycinat, Seekiefer-Rindenextrakt (Pinus pinaster), Mönchspfeffer-Extrakt, Pyridoxal-5'-phosphat, Cholecalciferol, Natrium-Riboflavin-5'-phosphat, Kupfercitrat, Thiaminmononitrat.
Directions & package
Take 2 capsules daily with plenty of liquid with a meal.
60 capsules · 30 days
Quality, lab & sources
Lab status: Lab report available
Product data checked on 16 Sep 2026.
Notes
Not suitable for persons under 18 years. Because the daily dose provides 10 mg vitamin B6, additional B6-containing products should be considered when assessing total intake.
Nutrient knowledge & reference values
Nutrient knowledge & reference values
General nutrient information for interpreting the product dosage. Signs of insufficient or excessive intake are non-specific and do not replace a diagnosis.
Magnesium
Magnesium is an essential mineral involved in numerous enzymatic reactions. For product assessment, the manufacturer’s dosage, active-ingredient forms and reference values are considered separately.
Functions
Magnesium contributes, among other things, to normal muscle and nerve function and to normal energy-yielding metabolic processes. It is also involved in processes related to protein, bone and DNA.
Possible signs of insufficient intake
Insufficient magnesium intake can present with nonspecific symptoms; possible indications may include neuromuscular complaints. Individual symptoms do not establish a diagnosis and should not be assessed in isolation.
Points to consider at high intake
High amounts from supplements can mainly cause gastrointestinal symptoms such as diarrhoea, nausea and abdominal cramps. With severely impaired kidney function, the risk of magnesium accumulation increases; high doses should then be medically assessed.
Special considerations
With impaired kidney function, magnesium excretion is reduced. Product dose, magnesium form, tolerance and total intake should therefore be considered separately.
Interactions / caution
Magnesium can affect the absorption of certain medicines, including some antibiotics and bisphosphonates. Timing intervals and individual medication should be reviewed with regular use.
Vitamin D3
Vitamin D is a fat-soluble vitamin and also a precursor of hormonally active metabolites. For the assessment of supplements, product dose, dosing interval, total intake, 25-OH-vitamin-D status and safety limits are considered separately.
Functions
EU-authorised functions include, among other things: vitamin D contributes to normal absorption and utilisation of calcium and phosphorus, normal blood calcium levels, the maintenance of normal bones and teeth, normal muscle function and normal functioning of the immune system. Vitamin D also has a role in the process of cell division.
Possible signs of insufficient intake
Inadequate vitamin D status cannot be reliably identified from individual nonspecific symptoms. For individual assessment, 25-OH-vitamin-D status together with exposure, diet and supplemental intake is more informative than symptoms alone.
Points to consider at high intake
A markedly excessive vitamin D intake over a prolonged period can lead to hypercalcaemia and hypercalciuria and thereby place a burden on the kidneys and other organ systems. Upper Intake Levels are safety limits for long-term intake and are not optimal target values.
Special considerations
Particular caution is required, among other situations, with diseases or therapies that affect calcium metabolism or kidney function. High doses should not be derived solely from general target values.
Interactions / caution
Vitamin D can interact with certain medicines; relevant examples include drugs that affect calcium or vitamin D metabolism. With prolonged higher-dose use, individual medication should be taken into account.
Zinc
Zinc is an essential trace element. The assessment considers the EU NRV, total intake, product dose and interactions—particularly with copper and medicines—separately.
Functions
EU-authorised health-claim functions include, among other things: zinc contributes to the normal function of the immune system, normal cognitive function, normal DNA synthesis, normal fertility and reproduction, and normal acid-base and carbohydrate metabolism. Zinc contributes to the maintenance of normal bones, hair, nails, skin and vision, protects cells from oxidative stress and has a role in the process of cell division.
Possible signs of insufficient intake
Zinc deficiency can be associated, among other things, with loss of appetite, impaired taste and smell, delayed wound healing, hair loss, growth impairment and increased susceptibility to infections. These symptoms are nonspecific and do not allow self-diagnosis.
Points to consider at high intake
Excessive zinc intake can cause nausea, vomiting, headaches and gastrointestinal symptoms. Chronically high amounts can inhibit copper absorption and thereby promote copper deficiency. The European EFSA/SCF UL for adults is 25 mg of zinc per day from total intake.
Special considerations
An increased risk of inadequate zinc intake exists, among other situations, with certain gastrointestinal diseases or after bariatric surgery, with strongly plant-based diets with low zinc bioavailability, during pregnancy and breastfeeding, and with chronically high alcohol consumption.
Interactions / caution
Zinc can reduce the absorption of quinolone and tetracycline antibiotics as well as penicillamine; dosing intervals should be observed. Thiazide diuretics can increase zinc excretion. Long-term high zinc intake can reduce copper absorption.
Copper
Copper is an essential trace element and a component of numerous enzyme systems. Product dose, total intake and the relationship with other trace elements—especially zinc—should be assessed separately.
Functions
EU-authorised health-claim functions include: copper contributes to the maintenance of normal connective tissues, normal energy-yielding metabolism, normal functioning of the nervous system and immune system, and the protection of cells from oxidative stress. It also contributes to normal iron transport in the body and to normal hair and skin pigmentation.
Possible signs of insufficient intake
Copper deficiency is rare. Reported signs include pronounced fatigue, abnormalities of connective tissue and bone, neurological symptoms, impaired coordination and increased susceptibility to infections. Diagnosis of deficiency requires professional assessment.
Points to consider at high intake
Chronically excessive copper intake can cause nausea, abdominal pain, vomiting, diarrhoea and liver damage, among other effects. The European EFSA/SCF UL for adults is 5 mg of copper per day from total intake. Special medical requirements apply in Wilson disease.
Special considerations
An increased risk of inadequate copper status may occur, among other situations, in coeliac disease, rare disorders of copper metabolism such as Menkes disease, and with long-term very high zinc intake. For people with Wilson disease, additional copper intake without medical supervision is not appropriate.
Interactions / caution
High zinc intake can reduce intestinal copper absorption and, with prolonged use, promote copper deficiency. No widespread clinically relevant drug interactions are established for copper; disease-specific situations such as Wilson disease require medical management.
Vitamin B6
Scientific assessment
Studies, meta-analyses and randomized controlled trials on the active ingredient – explained clearly and linked to sources.
AD1131373
The information is provided for factual classification of product and nutrient data. It does not replace medical diagnosis or individual treatment advice.
